Department of Chemistry & Biochemistry

Office:  C403 BNSN

Office Phone:  801-422-4054

Email:  safleming@chem.byu.edu

Education

BS University of Utah (1978)

Ph.D. University of Wisconsin (1984)

NIH Postdoctoral Fellow, Colorado State University (1984-86)

Visiting Professor, Florida State University (1993)
 

Research Interests

Synthesis of anticancer drugs and photoaffinity labeling for enzyme-substrate binding site determination.  Research ranges from enzyme interactions to targeted drug delivery, with a focus on mechanistic details of organic photochemistry.

Student Involvement/Requirements

 I will train 10 undergraduates in research positions.  Students in the research group learn tools that enhance their understanding of all areas of chemistry, including chemical principles related to cancer.   I begin taking undergraduates after they have completed Organic Chemistry or a Chemistry lab.  The work is publication oriented and undergraduates do appear on publications.  The source of funding is BYU.  A commitment to more than 3 semesters in the lab is preferred.

Publications

 Fleming, S. A., “Alkene + Alkene Photocycloaddition,” Synthetic Organic Photochemistry, Chapter 7, (2004).

Carroll, S., Fleming, S.A., Hirschi, J., Liu, R., Pace, J.L., Redd, J. T., “Asymmetric Dihydroxylation of Allenes,” Tetrahedron  Lett. 45, 3341-3343 (2004).

 Fleming, S.A., “Photocycloaddition of Alkenes to Excited Alkenes,” chapter in Synthetic Organic Photochemistry, A.G. Griesbeck and J. Mattay, eds., Marcel Dekker, New York, 141-160 (2004).